Genetron® AZ-20 (R-410A) is a high-performance, non-ozone-depleting HFC refrigerant blend developed by Honeywell to replace R-22 in new air conditioning and refrigeration systems. As an azeotropic blend of HFC-32 and HFC-125 (50/50 ratio), it delivers excellent thermal stability, zero glide, and high energy efficiency — making it the go-to refrigerant for next-generation residential and commercial cooling systems.
???? Not for retrofit use — specifically designed for new equipment only.
Applications:
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Residential Air Conditioners
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Commercial Air Conditioning Units
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Organic Rankine Cycle Systems
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High-Efficiency Heat Pumps and HVAC Systems
Technical Specifications:
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ASHRAE Number: R-410A
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Blend Type: Azeotropic HFC
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Composition: 50% HFC-32 (Difluoromethane), 50% HFC-125 (Pentafluoroethane)
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Boiling Point: –60.6 °F
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Critical Temperature: 160.4 °F
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Critical Pressure: 711 psia
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Molecular Weight: 72.6 lbm/lbmol
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Vapor Pressure (at 25°C): 239.6 psia
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Ozone Depletion Potential (ODP): 0
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Global Warming Potential (GWP): 2088
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Safety Classification (ASHRAE 34): A1 (non-flammable, non-toxic)
Lubricant Compatibility:
Requires POE (Polyol Ester) lubricants for optimal system performance.
Environmental & Safety Highlights:
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Zero ODP – environmentally friendly and compliant with global regulations
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ASHRAE A1 Rated – safe for human exposure, non-flammable
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High system efficiency with near-zero temperature glide for consistent cooling






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