Genetron® 407C (R-407C) is a non-ozone-depleting HFC refrigerant blend developed by Honeywell as a long-term replacement for HCFC-22 (R-22) in commercial, residential, and light industrial air conditioning systems. It is ideal for new equipment and retrofit applications, but is not recommended for flooded evaporator chillers due to its high glide characteristics.
Applications:
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Residential Air Conditioning
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Commercial Air Conditioning Systems
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Commercial Refrigeration
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Retrofit of R-22-based HVAC systems
Chemical Composition:
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HFC-32 (Difluoromethane) – 23%
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HFC-125 (Pentafluoroethane) – 25%
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HFC-134a (Tetrafluoroethane) – 52%
Technical Specifications:
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Type: HFC Blend
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ASHRAE Number: R-407C
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Molecular Weight: 86.2 lbm/lbmol
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Boiling Point: –46.5 °F (–43.6 °C)
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Critical Temperature: 186.9 °F (85 °C)
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Critical Pressure: 671.5 psia
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Liquid Density (at 86°F): 69.6 lb/ft³
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Lubricant Compatibility: Polyol Ester (POE)
Environmental & Safety:
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Ozone Depletion Potential (ODP): 0
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Global Warming Potential (GWP): 1774
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ASHRAE Safety Classification: A1 (Non-toxic, Non-flammable)
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Flammability Range in Air: None
Genetron® 407C delivers excellent cooling performance and efficiency in systems originally designed for R-22, making it a proven and cost-effective solution for environmentally conscious HVAC transitions.






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